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- Compact isolator
Compact isolator
A Grade A isolator in a benchtop footprint: working chamber, pass-through and ventilation inside a single monoblock of 160×76×100 cm. It serves where the process is small and the requirement is not: sterile handling, compounded preparations, quality control, laboratories that do not have a suite around them.
- Working chamber in Grade A — 80×70×60 cm at +80 Pa, with internal LAF filter and about 2,200 recirculations per hour
- Integrated pass-through — chamber 40×40×50 cm at +50 Pa with dedicated H14 filter: the central chamber is accessed only from there
- Two-stage filtration — synthetic-cell prefilter G4 and HEPA H14 on the compartment, H14 on the pass-through
- Siemens control with 7” touch panel — pressure switches on compartment and pass-through, filter clogging signalling. UV-C sanitisation available as an option, depending on the supply configuration
- +80 PaChamber overpressure
- 316LMirror stainless steel in product contact
- H14Compartment filtration
- 158 kgMachine weight
Pharmaceutical, biotechnology, medical, advanced therapies
Isolators designed around the process they must house, and qualified with the people who will work inside them.
The compact, up close
The machine from three-quarters, from the front, and with the side pass-through open.
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Compact stainless steel isolator, with two glove ports and side pass-through, three-quarter view. -
Compact stainless steel isolator, with two glove ports and side pass-through, front view. -
Compact stainless steel isolator, with two glove ports and side pass-through, with the side pass-through open.
A single machine,
and everything needed is already inside
The compact isolator has no range of sizes: it has one configuration, designed so that working chamber, pass-through, ventilation and controls fit in a single monoblock. There is one catalogue code, the rest are options.
- Chamber80×70×60 cm
The working compartment
Grade A at +80 Pa, about 2,200 recirculations per hour, airflow around 750 m3/h. Removable, sectionable floor and fixed containment tray for spills.
+80 Pa · 750 m3/h - Passbox40×40×50 cm
The only way in
+50 Pa, about 1,800 recirculations per hour and 150 m3/h, with a dedicated flat H14 filter. The configuration can have a single pass-through, or two, one inbound and one outbound.
+50 Pa · H14 - Footprint160×76×100 cm
How much space it needs
One metre sixty across the front, just over seventy centimetres deep, one metre high: it fits where a suite isolator never would. Weight 158 kg.
158 kg - FiltersG4 + H14
Two stages at the inlet
First stage synthetic cells G4 (305×610×60 mm), second stage HEPA H14 on the compartment (762×610×68 mm) and H14 on the pass-through. At the outlet, HEPA filter with optional activated carbon.
Optional carbon
External construction in AISI 304 satin Scotch-Brite stainless steel, TIG welded; the only part in contact with the product is a monoblock in AISI 316L mirror, rounded at all corners and polished so as not to retain dust. Power supply 220 V 50 Hz, installed power 1,100 W. The UV-C option is among the catalogue optionals; the number and power of the lamps are defined in the supply specification. The front glass is interlocked and does not open during handling: the product is touched only through the gloves.
Four choices that only show
when the machine is working
They are the same as in our large isolators, scaled down. None is visible in a photograph: all are felt at the first cleaning cycle and the first audit.
The monoblock, not the assembly
The product-contact chamber is made from a single TIG-welded piece with radiused corners throughout. There are no sharp edges or bolted joints: there is nowhere for dust to settle, and the polished surface is cleaned in a single pass.
316L mirror · TIGElectrically interlocked doors
The two pass-through doors cannot open together, and the status is read from outside with the indicator lights. The procedural error is seen before it is made, not in the next day’s minutes.
Electrical interlockConstant airflow, not fixed speed
Two centrifugal fans with inverter, controlled at constant airflow: as the filters load, the control compensates. The flow on the work surface stays what it was on the day of qualification, not what it was on the day of installation.
Inverter · Constant airflowThe removable floor and the tray
The internal work surface is removable and sectionable, and underneath there is a fixed containment tray for spills. It serves two purposes: cleaning properly, and not turning a spill into contamination of the machine.
Containment tray
Pressure is held by a damper,
not by goodwill
The working chamber has an internal LAF filter that maintains unidirectional flow over the zone. Two centrifugal fans with inverter work at constant airflow, and pressure switches monitor the state of the filters and the pressure in the working chamber and in the pass-through. Two modulating dampers regulate the pressure values set for the two compartments.
7” touch panel
All machine parameters are managed, adjusted and monitored from a single colour panel: pressures, airflows, filter status, internal power sockets, lamp.
Flow sensors
They regulate the fans, keeping the flow constant. Every value can be viewed and changed from the panel, and drift is read before it becomes a non-conformity.
Internal supervisor
Optional module: connected to the network, it allows our technician to intervene remotely. Less machine downtime, and no travel to put in the quote.
Six steps, one point of contact
It is the same path as a plant, to scale: what is looked at changes at each step, not who answers.
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01
Analyse
Process, standards and site constraints: from these come the class and the URS that fixes it.
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02
Design
Layout, separate flows, pressure cascade and HVAC, verified on BIM and CFD models.
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03
Manufacture
Panels, metalwork and control panels in our workshop, with factory acceptance testing (FAT).
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04
Install
On-site assembly, systems and monitoring, on-site verification (SAT) and start-up.
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05
Qualify
We carry out the tests and deliver audit-ready documentation, where required.
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06
Support
Scheduled maintenance, filters and calibration, including on systems built by others.
Where a compact isolator ends up
The criterion is not the sector, it is the volume of the process: when sterile processing takes up a work surface and not a room, the compact isolator costs and consumes an order of magnitude less than a suite.
Compounded preparations
Sterile preparations in hospital pharmacy and compounding, where the batch is the individual patient and there is no aseptic room.
HospitalQuality control and sterility testing
Sample handling in a Grade A environment, with the pass-through holding the separation between laboratory and chamber.
LaboratoryResearch and advanced therapies
Small-volume processing, where the process changes often and the machine must follow it without rebuilding the room.
Research
The regulatory framework we apply
The machine complies with the directives EU 2023/1230 and 2014/35/EU and with EN 61326-1:2021. The working chamber is qualified like any other Grade A: particle classification, filter integrity, recovery, and the glove leak test.
- EU GMP Annex 1
- EU GMP Annex 15
- ISO 14644-1
- ISO 14644-3
- ISO 14644-7
- ISO 14698-1
- EN 1822 · H13–U17
- EU 2023/1230
- 2014/35/EU
- EN 61326-1:2021
What we get asked before signing
Do I need a cleanroom around it?
No, and that is the reason it exists: the isolator holds its Grade A on its own. The room that houses it must still be kept under control, but it does not have to be a classified room. Which classification the room needs is decided by the risk analysis of your process, not by the machine.
Can I have two pass-throughs, one inbound and one outbound?
Yes. The configuration can have a single pass-through, used for both entry and exit, or two, one for each direction. The second choice separates the flows, and is worth it every time outgoing material must not cross incoming material.
How is it sanitised?
UV-C sanitisation is available as an option, depending on the supply configuration: the catalogue lists it among the optionals without specifying the number of lamps. For processes requiring a validatable bio-decontamination the machine is prepared for vaporised hydrogen peroxide: surfaces, seals and materials are already chosen to withstand the cycles.
What is the difference from the isolators in the large range?
The class is the same, Grade A. What changes are the working volume, the number of gloves and the fact that here the pass-through is integrated in the monoblock instead of being a modular unit. If the processing takes up more than one work surface the right answer is thepositive pressure isolator; if you need to protect the operator rather than the product, thenegative pressure isolator.
Can it be moved?
It is a 158 kg machine on a front of one metre sixty: it can be moved, but it is not a trolley. It must be positioned where it will stay, with the power supply and, if provided, the exhaust ducting.
Tell us about the process,
we will configure the machine
What is handled, how long it stays exposed, how it enters and how it leaves, and what your contamination control strategy requires. With these elements the configuration comes out at the first pass, and the quote is built on your process, not on a price list.
